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Dipl.-Chem. Susanne Feineis


Main research

Plasmon-resonant gold nanorods (Au NRs) possess absorption bands located in the near-infrared region, which afford a very efficient photo-thermal conversion. Controlled surface modifications with biomolecules and drugs turn Au NRs into suitable systems for drug-delivery. Hence nanorods are excellent candidates as multifunctional agents for a laser-induced treatment of tumors and temperature-controlled drug-release.

Polymer- and biofunctionalized gold nanoparticles for laser-induced cell manipulation

In the context of the phototherapy of tumors, polymer-coated Au NRs are functionalized with cell-binding ligands. Thus these modified Au NRs attach selectively to tumor cells and subsequent laser irradiation leads to apoptosis of the labeled cells-types. With regard to drug release, siRNA-modified Au NRs are introduced into cells and temperature-controlled drug-release can take place for the polymer protected drug substances.

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